Anagram & Information om | Engelska ordet ACARBOSE
ACARBOSE
Antal bokstäver
8
Är palindrom
Nej
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Exempel på hur man kan använda ACARBOSE i en mening
- The effects of pioglitazone have been compared in a Cochrane systematic review to that of other blood sugar lowering-medicine, including metformin, acarbose, and repaglinide, as well as with appropriate diet and exercise, not showing any benefit in reducing the chance of developing type 2 diabetes in people at risk.
- It was found that acarbose reduced the incidence of diabetes mellitus type 2 when compared to placebo, however there was no conclusive evidence that acarbose, when compared to diet and exercise, metformin, placebo, or no intervention, improved all-cause mortality, reduced or increased risk of cardiovascular mortality, serious or non-serious adverse events, non-fatal stroke, congestive heart failure, or non-fatal myocardial infarction.
- Moreover, acarbose inhibits pancreatic alpha-amylase in addition to alpha-glucosidase, and is degraded by gut bacterial maltogenic alpha-amylase and cyclomaltodextrinase.
- In contrast to acarbose (another alpha-glucosidase inhibitor), miglitol is systemically absorbed; however, it is not metabolized and is excreted by the kidneys.
- There are three major drugs which belong to this class, acarbose, miglitol and voglibose, of which voglibose is the newest.
- Metformin and acarbose help prevent the development of prediabetes, and also have a good safety profile.
- This class includes acarbose, validamycin, validoxylamine A, salbostatin, cetoniacytone A, pyralomicin 1a, kirkamide.
- Valienamine is a C-7 aminocyclitol found as a substructure of pseudooligosaccharides such as the antidiabetic drug acarbose and the antibiotic validamycin.
- It was found that acarbose appeared to reduce incidence of diabetes mellitus type 2 when compared to placebo; however, there was no conclusive evidence that acarbose compared to diet and exercise, metformin, placebo, no intervention improved all-cause mortality, reduced or increased risk of cardiovascular mortality, serious or non-serious adverse events, non-fatal stroke, congestive heart failure, or non-fatal myocardial infarction.
- The 3D structure of the pseudo-tetrasaccharide acarbose complexed with glucoamylase II(471) from Aspergillus awamori var.
- Actinoplanes species produce the pharmaceutically important compounds valienamine (a precursor to the antidiabetic drug acarbose and to the antibiotic validamycin), teicoplanin, and ramoplanin.
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