Information om | Engelska ordet ACETYLTRANSFERASES

Exempel på hur man kan använda ACETYLTRANSFERASES i en mening

• Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl-CoA to form ε-N-acetyllysine.
• These modifications are effected by enzymes called histone acetyltransferases (HATs) and histone deacetylases (HDACs).
• Once activated by nitric oxide, GAPDH binds to the ubiquitin ligase SIAH1, and is transported to the nucleus where it activates the acetyltransferases p300/CBP to enhance acetylation and subsequent transcription.
• The encoded protein may also act as a general coactivator since it has been shown to interact with some basal transcription factors, histone acetyltransferases, and methyltransferases.
• Mechanistically, KMT2C and KMT2D are required for the binding of H3K27 acetyltransferases CREB-binding protein (CBP) and/or p300 on enhancers, enhancer activation, and enhancer-promotor looping prior to gene transcription.
• These are histone acetyltransferases and histone deacetylases which activate and repress genes involved in the myocyte lineage.
• Interaction of E1A with p300/CBP histone acetyltransferases causes a reduction in total cellular acetylation of H3K18 by roughly a factor of 3, which may be similar in mechanism to nonviral forms of oncogenesis.
• Peregrin is a multivalent chromatin regulator that recognizes different epigenetic marks and activates three histone acetyltransferases (Moz, Morf and Hbo1).
• Polycomb protein YY1 is believed to mediate the activity of histone deacetylases and histone acetyltransferases to facilitate chromatin re-organization; this is often to facilitate the formation of heterochromatin (gene-silencing state).

Förberedelsen av sidan tog: 111,68 ms.