Information om | Engelska ordet BIFUNCTIONAL

Exempel på hur man kan använda BIFUNCTIONAL i en mening

• The enzyme can also be found in a bifunctional form consisting of an N-terminal aspartokinase domain and a C-terminal homoserine dehydrogenase domain, as found in bacteria such as Escherichia coli and in plants.
• Acetylacetone is a versatile bifunctional precursor to heterocycles because both keto groups may undergo condensation.
• The bifunctional protein NCOAT (nuclear cytoplasmic O-GlcNAcase and acetyltransferase) that is encoded by the MGEA5 gene possesses both hexosaminidase and histone acetyltransferase activities.
• The kinase domain is responsible for the autophosphorylation of the histidine with ATP, the phosphotransfer from the kinase to an aspartate of the response regulator, and (with bifunctional enzymes) the phosphotransfer from aspartyl phosphate to water.
• OGG1 is a bifunctional glycosylase, as it is able to both cleave the glycosidic bond of the mutagenic lesion and cause a strand break in the DNA backbone.
• These compounds are of interest because they are bifunctional: the vinyl group is susceptible to polymerization and the carboxylate group carries myriad functionalities.
• This is a bifunctional membrane/RNA-binding protein that mediates the encapsidation of nucleoprotein cores into the membrane envelope.
• Polynucleotide Phosphorylase (PNPase) is a bifunctional enzyme with a phosphorolytic 3' to 5' exoribonuclease activity and a 3'-terminal oligonucleotide polymerase activity.
• Lomustine is a bifunctional alkylating agent, alkylates both DNA and RNA, has the ability to created interstrand cross-links (ICLs) in DNA.
• The crosslinking density of melamine resins can be controlled by co-condensation with bifunctional analogues of melamine, benzoguanamine and acetoguanamine.
• This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes.
• In yeast, GARS is part of a bifunctional enzyme (encoded by the ADE5/7 gene) in conjunction with phosphoribosylformylglycinamidine cyclo-ligase (AIRS).
• Also several studies have proven the bifunctional tumor suppressor/oncogene role of TGF beta signaling pathway in carcinogenesis.
• In particular, it has been shown that the Acinetobacter calcoaceticus ADP1 strain synthesizes wax esters through a bifunctional wax ester synthase/acyl-CoA: diacylglycerol acyltransferase (WS/DGAT) and that this complex can be functionally expressed in different bacterial hosts, suggesting the potential for potential microbial production of cheap jojoba-like wax esters.
• This bifunctional enzyme has been identified as a druggable target for malarial parasites, and high-throughput screening of small molecule inhibitors has resulted in the discovery of novel compounds that can potentially be translated into potent antimalarials.
• Some sulfate adenylyltransferases are part of a bifunctional polypeptide chain associated with adenosyl phosphosulfate (APS) kinase.
• Because of its bifunctional nature, having two amino groups, it readily forms heterocycles such as imidazolidines.
• Formimidoyltransferase cyclodeaminase or formiminotransferase cyclodeaminase (gene symbol FTCD in humans) is a bifunctional enzyme that catalyzes the following reactions:.
• Studies in multiple organisms including, mice, rats, chicks, the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster and the zebrafish Danio rerio have indicated that secreted netrins are bifunctional, meaning that they can act as either attractants or repellants in directing axonal extension.
• Monofunctional glycosylases have only glycosylase activity, whereas bifunctional glycosylases also possess AP lyase activity.

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