Information om | Engelska ordet BIOAVAILABLE

Exempel på hur man kan använda BIOAVAILABLE i en mening

• Many herbal extracts historically used in medicine contain glycosides (sugar derivatives) of the active agent, which are hydrolyzed in the intestines to release the active and more bioavailable aglycone.
• Additionally, marketers have inaccurately claimed that the process of electrolysis changes the structure of water from large non-bioavailable water clusters to small bioavailable water clusters, called "micro clusters".
• After host lysis, new phages trigger a new infection cycle with surrounding bioavailable host species resulting in growth and expansion.
• Thus, lead-containing surma consists of inhalable and bioavailable particles, and it contributes to an increased risk of lead exposure.
• Ellagic acid has low bioavailability, with 90% remaining unabsorbed from the intestines until metabolized by microflora to the more bioavailable urolithins.
• Proanthocyanidins, including the lesser bioactive and bioavailable polymers (four or more catechins), represent a group of condensed flavan-3-ols, such as procyanidins, prodelphinidins and propelargonidins.
• reported advances in the diffusive gradients in thin films technique, which have provided a method to measure labile bioavailable americium in soils, as well as in freshwater and seawater.
• Like nitrogen, plants require these substances to live but they must be contained in other chemical substances such as monoammonium phosphate or diammonium phosphate to serve as bioavailable nutrients.
• Batimastat (codename BB94) progressed as far as stage 3 in its clinical trial, although not orally bioavailable, there are other methods of administration, including transdermal.
• recently reported advances in the Diffusive gradients in thin films technique, which have provided a method to measure labile bioavailable Plutonium in soils, as well as in freshwater and seawater.
• Procyanidins, including the lesser bioactive / bioavailable polymers (4 or more catechines), represent a group of condensed flavan-3-ols that can be found in many plants, most notably apples, maritime pine bark, cinnamon, aronia fruit, cocoa beans, grape seed, grape skin, and red wines of Vitis vinifera (the common grape).
• UFT is an oral formulation combining uracil (a competitive inhibitor of dihydropyrimidine dehydrogenase), and tegafur (a bioavailable 5-fluorouracil (5-FU) prodrug) in a 4:1 molar ratio.
• Eelgrass beds are found in the intertidal and subtidal mudflats, and biologically interact with oyster beds in a few ways: The pseudofeces and feces of bivalves have been found to fertilize seagrass by increasing bioavailable macronutrients such as ammonium and phosphate in sediments.
• In particular, Gilead Sciences in the United States developed a carbocyclic, orally bioavailable neuraminidase inhibitor currently marketed under the name Tamiflu.
• In the design process of nelfinavir, an orally bioavailable and nonpeptidic inhibitor, iterative protein cocrystal structure analysis of peptidic inhibitors was used and parts of the inhibitors were replaced by nonpeptidic substituents.
• Crenolanib is an orally bioavailable benzimidazole that selectively and potently inhibits signaling of wild-type and mutant isoforms of class III receptor tyrosine kinases (RTK) FLT3 (FMS-like Tyrosine Kinase 3), PDGFR α (Platelet-Derived Growth Factor Receptor), and PDGFR β.
• JNJ-38877605, which contains a difluoro methyl linker and a bioavailable quinoline group, was undergoing clinical trials of Phase I for advanced and refractory solid tumours in 2010.
• In neuropsychopharmacology, uncoupling, also known as decoupling, is the process of receptor- or ligand-binding sites or domains becoming separated, moving alignments and/or becoming internalised as a result of drug tolerance resulting from prolonged exposure to bioavailable psychoactive substances or toxins.
• Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor based on hydroxamic acid with potential anti-tumor activity characterized by favorable physicochemical, pharmaceutical, and pharmacokinetic properties.
• Resminostat (4SC-201 or RAS2410) is an orally bioavailable inhibitor of histone deacetylases (HDACs), of which inhibitors are antineoplastic agents.

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