Information om | Engelska ordet CHIMERIC

Exempel på hur man kan använda CHIMERIC i en mening

• Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases.
• It is a chimeric mutation of Pinot: its inner cell layers are composed of a Pinot genotype which is close to Pinot noir or Pinot gris; the outer, epidermal, layer is, however, made up of a mutant, distinctive, genotype.
• The first specimen to be described was part of a chimeric specimen—a patchwork of different feathered dinosaur species (Microraptor itself, Yanornis and an as-of-yet undescribed third species) assembled from multiple specimens in China and smuggled to the USA for sale.
• In late 2017, LLS awarded researchers at UNC School of Medicine a $600,000 grant to support clinical research on chimeric antigen receptor (CAR) T cell therapies with an immunosuppressive "safety switch".
• Recombinant DNA molecules are sometimes called chimeric DNA because they can be made of material from two different species like the mythical chimera.
• This work prompted CD3ζ intracellular domains to be added to chimeric receptors with antibody-like extracellular domains, commonly single-chain fraction variable (scFv) domains, as well as proteins such as CD4, subsequently termed first generation CARs.
• CPT uses a sequence specific chimeric probe which hybridizes to a complementary target DNA sequence and becomes a substrate for RNase H.
• 2011 The 6th Albert Szent-Györgyi Prize for Progress in Cancer Research was awarded to Beatrice Mintz by the National Foundation for Cancer Research for her discoveries of the relationship between development and cancer, based on construction and analysis of chimeric and transgenic mouse models.
• Urokinase receptors have been found to be highly expressed on senescent cells, leading researchers to use chimeric antigen receptor T cells to eliminate senescent cells in mice.
• It has had a confusing history, being considered both a hadrosaurid and a ceratopsid, or both at the same time (chimeric).
• Examples of chimeric antibodies approved for human therapy include abciximab (ReoPro), basiliximab (Simulect), cetuximab (Erbitux), infliximab (Remicade) and rituximab (MabThera).
• hislopi was based on a chimeric syntype material - a rhynchosaurian basicranium mixed with phytosaurian partial snout, scutes and some teeth.
• However, Lydekker's description was based on a chimeric syntype, combining fossils from multiple unrelated reptiles: a rhynchosaurian basicranium mixed with the partial snout of a phytosaur, scutes and some teeth.
• Other viral chimeras have also been found, and the group is known as the CHIV viruses ("chimeric viruses").
• The relationship between the structure and function of P2X receptors has been the subject of considerable research using site-directed mutagenesis and chimeric channels, and key protein domains responsible for regulating ATP binding, ion permeation, pore dilation and desensitization have been identified.
• Thus, the human/mouse chimeric antibody basiliximab ends in -ximab just as does the human/macaque antibody gomiliximab.
• This was initially achieved by the production of chimeric (suffix -ximab) and humanized antibodies (suffix -zumab).
• Volociximab (also known as M200) is a chimeric monoclonal antibody jointly developed by PDL BioPharma and Biogen Idec for treatment of a variety of advanced solid tumors.
• Examples include chimeric and humanized minretumomab, as well as a fusion protein of a minretumomab single-chain variable fragment and the enzyme beta-lactamase.
• George Albert Boulenger placed Meiolania in Pleurodira and Arthur Smith Woodward officially split the chimeric hypodigm of Megalania into monitor lizard, marsupial and turtle remains, with the name being constrained to the lizard.

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