Information om | Engelska ordet CHOLINERGIC

Exempel på hur man kan använda CHOLINERGIC i en mening

• An acetylcholine receptor (abbreviated AChR) or a cholinergic receptor is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.
• Edrophonium (by the so-called Tensilon test) is used to differentiate myasthenia gravis from cholinergic crisis and Lambert-Eaton.
• It works by activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to open and the aqueous humor to drain from the eye.
• In very serious cases of hyperhidrosis, a solution containing glycopyrronium bromide or glycopyrrolate, a cholinergic inhibitor, can be used.
• Tacrine is a centrally acting acetylcholinesterase inhibitor and indirect cholinergic agonist (parasympathomimetic).
• The rodent whisker barrel efforts became a focus for Ebner, Matthew Diamond, Michael Armstrong-James, Robert Sachdev, Kevin Fox and great inroads were made in identifying the locus of change as being at cortical synapses expressing NMDA receptors, and in implicating cholinergic inputs as necessary for normal expression.
• Nefiracetam's cytoprotective actions are mediated by enhancement of GABAergic, cholinergic, and monoaminergic neuronal systems.
• The symptoms of a cholinergic toxidrome include bronchorrhea, confusion, defecation, diaphoresis, diarrhea, emesis, lacrimation, miosis, muscle fasciculations, salivation, seizures, urination and weakness.
• Meclofenoxate (INN, BAN; brand name Lucidril, also known as centrophenoxine) is a cholinergic nootropic used as a dietary supplement.
• It is to be noted, further, that in the cases for which direct evidence is already available, the phenomena of regeneration appear to indicate that the nature of the chemical function, whether cholinergic or adrenergic, is characteristic for each particular neurone, and unchangeable.
• They initially provoke a transitory stimulation of nicotinic cholinergic receptors followed by a persistent inhibition caused by desensitization.
• The laterodorsal tegmental nucleus (LDT) sends cholinergic (acetylcholine) projections to many subcortical and cortical structures, including the thalamus, hypothalamus, substantia nigra (dopamine neurons), ventral tegmental area (dopamine neurons), cortex (with bidirectional connections with the prefrontal cortex).
• It has two divisions of subnuclei; the pars compacta, containing mainly cholinergic neurons, and the pars dissipata, containing mainly glutamatergic neurons and some non-cholinergic neurons.
• In 1987, Bartolini and colleagues reported progabide's actions on dopamine to be contradictory, decreasing dopamine release, dopamine receptor density and postsynaptic receptor responsivity to dopamine while reducing striatal cholinergic activity so as to increase dopaminergic effects.
• Preganglionic fibers originate from the Edinger–Westphal nucleus, travel along the oculomotor nerve (CN III), and make nicotinic cholinergic synapses on neurons in the ciliary ganglion.
• Trimetaphan is a ganglionic blocker: it counteracts cholinergic transmission at a specific type of nicotinic acetylcholine receptors in the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathetic nervous system.
• Testing with low dose (1/8%) pilocarpine may constrict the tonic pupil due to cholinergic denervation supersensitivity.
• As a result of cholinergic crisis, the muscles stop responding to the high synaptic levels of ACh, leading to flaccid paralysis, respiratory failure, and other signs and symptoms reminiscent of organophosphate poisoning.
• Binding studies indicate that it has no effect on monoamine uptake and no affinity for adrenergic, histamine, cholinergic, dopamine, and benzodiazepine receptors, nor other serotonin receptors.
• Involvement of the basolateral amygdala in muscarinic cholinergic modulation of extinction memory consolidation.

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