Information om | Engelska ordet CLOFAZIMINE

Exempel på hur man kan använda CLOFAZIMINE i en mening

• Dapsone, also known as 4,4'-sulfonyldianiline (SDA) or diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.
• Myoconda, the company's lead product, is a combination of the antibiotics rifabutin, clarithromycin and clofazimine.
• In China, dapsone was used from 1946 to treat leprosy, but treatment of the disease took a leap in 1982 with the introduction of a largely successful multidrug therapy (MDT) using dapsone, rifampicin, and clofazimine.
• Furthermore, clofazimine in combination with the antibiotics clarithromycin and rifabutin induced remission for about 2 years in patients with Crohn's disease, but the effect was temporary; the effect was thought to be due to anti-mycobacterial activity, but could well have been an immunomodulatory effect by clofazimine.
• Recently, through drug repurposing, a strategy which utilizes existing drugs for new therapeutic purposes, the trypanocidal effects of benidipine and clofazimine have been discovered.
• The handling of these cases is debatable, with differing results from topical treatments using tacrolimus, retinoids, and corticosteroids, and systemic treatments using methotrexate, isotretinoin, clofazimine, acitretin, and hydroxychloroquine.
• Contrary to popular belief, both forms of leprosy are curable, with the lepromatous form classically treated with antibiotics dapsone, rifampin and clofazimine for as long as 2–5 years, but if left untreated the person may die up to 20 or 30 years from its inception.
• Lucio's phenomenon is treated by anti-leprosy therapy (dapsone, rifampin, and clofazimine), optimal wound care, and treatment for bacteremia, including antibiotics.
• Lucio's phenomenon is treated by anti-leprosy therapy (dapsone, rifampin, and clofazimine), optimal wound care, and treatment for bacteremia including antibiotics.

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