Definition & Betydelse | Engelska ordet DEPOLARIZES

Definition av DEPOLARIZES

1. böjningsform av depolarize

Exempel på hur man kan använda DEPOLARIZES i en mening

• In the dark, a photoreceptor (rod/cone) cell will release glutamate, which inhibits (hyperpolarizes) the ON bipolar cells and excites (depolarizes) the OFF bipolar cells.
• Bending the stereocilia toward the kinocilium depolarizes the cell and results in increased afferent activity.
• An activation of smooth muscle cells through caffeine activates ryanodine receptors of the sarcoplasmic reticulum, whereas an activation through high levels of extracellular potassium depolarizes the membrane (due to the change of the reversal potential for potassium towards more positive values) and would then activate voltage-gated calcium-ion channels leading to high levels of intracellular calcium ions.
• While the sinoatrial node typically regulates the heartbeat during normal sinus rhythm, PACs occur when another region of the atria depolarizes before the sinoatrial node and thus triggers a premature heartbeat, in contrast to escape beats, in which the normal sinoatrial node fails, leaving a non-nodal pacemaker to initiate a late beat.
• This depolarizes the muscle fiber membrane, and the impulse travels to the muscle's sarcoplasmic reticulum via the transverse tubules.
• When extracellular cardioplegia displaces blood surrounding myocytes, the membrane voltage becomes less negative and the cell depolarizes more readily.
• In the process of binding, decamethonium activates (depolarizes) the motor endplate - but since the decamethonium itself is not degraded, the membrane remains depolarized and unresponsive to normal acetylcholine release.
• It has been shown that ghrelin, a hormone involved with initiation of a hunger state, depolarizes and activates orexin cells.

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