Synonymer & Information om | Engelska ordet DOCETAXEL

Exempel på hur man kan använda DOCETAXEL i en mening

• In July 2014 published results of a phase 2 trial (for NSCLC) concluded : "The addition of PX-866 to docetaxel did not improve PFS, response rate, or OS in patients with advanced, refractory NSCLC without molecular preselection".
• Scalp cooling has specifically been used to prevent alopecia in docetaxel chemotherapy, although it has been found prophylactic in other regimens as well.
• Conjunctive treatment of prednisone with docetaxel has been shown to lead to improved survival rate as well as improved quality of life and reduction of pain compared with treatments with mitoxantrone.
• In context of lung cancer drug development, the cells have served as testing grounds for novel drugs - such as paclitaxel, docetaxel, and bevacizumab - both in vitro and in vivo through cell culture and xenografting, respectively.
• Pertuzumab, sold under the brand name Perjeta, is a monoclonal antibody used in combination with trastuzumab and docetaxel for the treatment of metastatic HER2-positive breast cancer; it also used in the same combination as a neoadjuvant in early HER2-positive breast cancer.
• Examples of mitotic inhibitors frequently used in the treatment of cancer include paclitaxel, docetaxel, vinblastine, vincristine, and vinorelbine.
• They are mitomycin C, cisplatin, carboplatin, oxaliplatin, irinotecan, 5-fluorouracil, gemcitabine, paclitaxel, docetaxel, doxorubicin, premetrexed, and melphalan.
• Laniquidar has been tested for its efficacy for treating refractory breast cancer together with docetaxel and paclitaxel.
• TCH is a chemotherapy regimen consisting of Taxotere (docetaxel), carboplatin and Herceptin (trastuzumab), which is used to treat breast cancer.
• In December 2014, the FDA approved ramucirumab in combination with docetaxel for treatment of metastatic non-small-cell lung carcinoma (NSCLC) with disease progression during or after first-line platinum-containing chemotherapy.
• Exudative hyponychial dermatitis is a nail toxicity common during chemotherapy for breast cancer, especially if docetaxel is the chemotherapeutic regimen.
• Scleroderma-like reaction to taxanes may occur in patients treated with docetaxel or paclitaxel, characterized by an acute, diffuse, infiltrated edema of the extremities and head.
• In addition to doxorubicin, RGD-conjugated nanomaterials have been used to deliver the chemotherapeutics cisplatin, docetaxel, paclitaxel, 5-fluorouracil, and Gemcitabine to cancer cells.
• the combination of docetaxel, neoadjuvant hormonal therapy (NHT), and androgen deprivation therapy (ADT) used to treat high volume metastatic hormone sensitive prostate cancer (mHSPC).
• Preclinically, tesetaxel demonstrated substantially higher activity against cancer cell lines that were resistant to paclitaxel and docetaxel, since acquired resistance to this drug class is not mediated by the multidrug-resistant p-glycoprotein.
• In people with metastatic castration-resistant prostate cancer (mCRPC), overall survival (OS) is markedly enhanced with cabazitaxel versus mitoxantrone after prior docetaxel treatment.
• The taxoids class and the taxanes class both include paclitaxel (trade names Taxol, Abraxane, Onxol, Nov-Onxol) and docetaxel (trade names Taxotere, Docecad).
• In the United States, trastuzumab emtansine was approved specifically for treatment of HER2-positive metastatic breast cancer (mBC) in patients who have been treated previously with trastuzumab and a taxane (paclitaxel or docetaxel), and who have already been treated for mBC or developed tumor recurrence within six months of adjuvant therapy.
• Navitoclax as mono-therapy as well as in combination with chemotherapies (paclitaxel, docetaxel, gemcitabine, and irinotecan), olaparib, erlotinib, venetoclax, and rituximab in advanced hematological malignancies (in both pediatric and adult patients) and solid tumors including ovarian cancer, breast cancer, lung cancer.
• This effect has been observed with dexamethasone, the anti-cancer drugs docetaxel and etoposide, and to a minor (not clinically significant) extent with levonorgestrel, erythromycin and midazolam.

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