Information om | Engelska ordet GVHD

Exempel på hur man kan använda GVHD i en mening

• The white blood cells present within the transplanted tissue then attack the recipient's body's cells, which leads to GvHD.
• Mortality is higher in TA-GvHD than in GvHD associated with bone marrow transplantation, where the engrafted lymphoid cells in the bone marrow are of donor origin (in autotransplant) and therefore the immune reaction is not directed against them.
• DNAM-1 interaction with its ligands promotes killing of immature and mature dendritic cells, is involved in the crosstalk between NK cells and T lymphocytes and can lyse activated T lymphocytes during graft versus host disease (GvHD).
• Histone deacetylate inhibitors (HDACi) can suppress proinflammatory cytokine production and reduce GvHD.
• It is closely linked with graft-versus-host disease (GvHD), as the underlying principle of alloimmunity is the same.
• It has entered clinical trials for acute myeloid leukaemia (AML), chronic lymphocytic leukemia (CLL), diffuse large B cell lymphoma (DLBCL), graft-versus-host disease (GvHD), hematological malignancies, mantle cell lymphoma (MCL), and non-Hodgkin lymphoma (NHL).

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