Anagram & Information om | Engelska ordet INDOMETACIN

Exempel på hur man kan använda INDOMETACIN i en mening

• It was derived from propionic acid by the research arm of Boots UK during the 1960s, a period which also included the discovery of ibuprofen, indometacin, diclofenac, naproxen, ketoprofen, and sulindac.
• Indometacin farnesil (INN) is a prodrug of the nonsteroidal anti-inflammatory drug (NSAID) indometacin, designed to reduce the occurrence of side-effects by esterification of the carboxyl group on indometacin with farnesol.
• In patients with rheumatoid arthritis or osteoarthritis tolmetin was as effective as aspirin and indometacin, although the occurrence of mild gastrointestinal adverse effects and tinnitus was lower in patients treated with tolmetin than it was with aspirin-treated patients and the occurrence of adverse effects of the central nervous system was lower with tolmetin than it was with indomethacin.
• It is metabolized in the body to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.
• An advantage of acemetacin is that it reduces gastric damage as compared to indometacin, possibly because acemetacin has less effect on the increase of leukotriene B4 synthesis and tumor necrosis factor (TNF) expression, leading to less induction of leukocyte-endothelial adherence.
• Medications – chemotherapy, sulfas or other antibiotics, phenothiazines, benzodiazepines, antithyroid medications, anticonvulsants, quinine, quinidine, indometacin, procainamide, thiazides.
• Prostaglandin F synthase can be inhibited not only by NSAIDs such as indometacin and suprofen but also by a molecule known as bimatoprost (BMP).

Förberedelsen av sidan tog: 226,31 ms.