Information om | Engelska ordet IPRGCS

Exempel på hur man kan använda IPRGCS i en mening

• The human eye contains three types of photoreceptors, rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs).
• In 2002 Brown University researchers led by David Berson announced the discovery of special cells in the human eye, ipRGCs (intrinsically photosensitive retinal ganglion cells), which many researchers now believe control the light entrainment effect of the phase response curve.
• Intrinsically photosensitive retinal ganglion cells (ipRGCs), also called photosensitive retinal ganglion cells (pRGC), or melanopsin-containing retinal ganglion cells (mRGCs), are a type of neuron in the retina of the mammalian eye.
• The axons of the ipRGCs belonging to the retinohypothalamic tract project directly, monosynaptically, to the suprachiasmatic nuclei (SCN) via the optic nerve and the optic chiasm.
• Ultimately, via this retinohypothalamic tract (RHT) the suprachiasmatic nucleus (SCN) of the hypothalamus receives light information from these ipRGCs.
• Czeisler has also dedicated a portion of his career to examining the effects of light timing, duration, intensity, and wavelength on resetting the pacemaker through ipRGCs, which contain the photopigment melanopsin.
• He is credited with discovering that the photopigment melanopsin and associated ipRGCs play an important role in the entrainment of circadian rhythms.
• Later, it was found that this novel photopigment, melanopsin, plays an important role in non-visual responses to light within the human body and is present in a distinct class of photoreceptor cells called intrinsically photosensitive retinal ganglion cells (ipRGCs).
• Results from whole-cell recordings of ipRGC membrane voltage in response to white-light stimuli demonstrated that ipRGCs shift from relying solely on intrinsic phototransduction before mice open their eyes to relying on intrinsic and extrinsic phototransduction after eye-opening.

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