Synonymer & Information om | Engelska ordet LAPATINIB

Exempel på hur man kan använda LAPATINIB i en mening

• The safety and efficacy of trastuzumab-containing combination therapies (with chemotherapy, hormone blockers, or lapatinib) for the treatment of metastatic breast cancer.
• Food and Drug Administration (FDA) approved lapatinib in combination therapy for breast cancer patients already using capecitabine (Xeloda).
• He was involved in the clinical development of targeted drugs for cancer including cetuximab, pertuzumab, trastuzumab and lapatinib.
• Like lapatinib and neratinib, afatinib is a protein kinase inhibitor that also irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.
• Like lapatinib and afatinib, it is a dual inhibitor of the human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.
• There have also been reports of drug-induced tufted hair folliculitis associated with the use of cyclosporin, trastuzumab, and lapatinib.
• Currently, solid preclinical studies have been carried out with second-generation inhibitors combined with afatinib, erlotinib and lapatinib.
• Important role (David Cameron as joint global Chief Investigator) in the pivotal clinical trial that tested the hypothesis that the combination of lapatinib and the cytotoxic drug capecitabine would be superior to capecitabine alone in patients with HER2+ metastatic breast cancer that had progressed despite trastuzumab treatment.
• In a preclinical study, copanlisib was effective in inhibiting HER2+ breast cancer cells with acquired resistance to the HER2-inhibitors trastuzumab and/or lapatinib.

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