Synonymer & Information om | Engelska ordet LD50

Exempel på hur man kan använda LD50 i en mening

• Prednisolone acetate is acutely toxic with an LD50 of >240 mg/kg for a rat and 3500 mg/kg for a mouse.
• Smaller doses have been shown to cause seizures, salivation, muscle contractions, dyspnoea and death in mice: the subcutaneous LD50 is just 0.
• It was unappreciated at the time but the average radiation dose that would kill approximately 50 percent of adults (the LD50) was approximately halved; that is, smaller doses were made more lethal when the individual experienced concurrent blast or burn polytraumatic injuries.
• Tertiapin is a compound of the honey bee venom (apitoxin) that causes pain and signs of inflammation around the sting, but a great number of stings can be lethal (LD50 is 18-22 stings per kg for humans).
• The LD50 of AETX K is not known so far, but its 50% inhibitory concentration (IC50) was determined as 91 nM.
• Oleylamine has an LD50 (Intraperitoneal) of 888  mg/kg in mice, however, note that it is listed as a level 3 health hazard on the NFPA diamond, so it should be handled with caution.
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• Animal tests performed include the Draize eye irritancy test, where test chemicals are applied to rabbits’ eyes and left on for several days, and toxicity tests such as LD50, where a substance's toxicity is tested by determining the concentration at which it will kill 50% of the test animals.
• The related methyl and butyl methacrylates have respective acute LD50s 10 and 20 g/kg (oral, rat); a linear extrapolation suggests that ethyl methacrylate would have LD50 approximately 13 g/kg.
• According to the estimated LD50 of 3906 mg/kg, methyl isonicotinate is classified as category V on GLP criteria for acute oral toxicity.
• While Phoneutria nigriventer venom is highly neurotoxic and can cause a range of symptoms that may include agitation, hypertension, perspiration, excessive salivation, nausea, profuse vomiting, lacrimation, somnolence, tachycardia, tachypnea, spasms, tremors, and priapism, the toxicity of Phα1β has not been sufficiently characterized to provide estimates of its LD50 or specific side effects.

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