Information om | Engelska ordet MODAFINIL

Exempel på hur man kan använda MODAFINIL i en mening

• Smart shops (often webshops) offer prescription-free pharmacy products such as Ritalin, Adderall, and modafinil, for example.
• Adrafinil is a prodrug; it is primarily metabolized in vivo to modafinil, resulting in very similar pharmacological effects.
• After being confronted with evidence seized from BALCO, she admitted using tetrahydrogestrinone (THG) and erythropoietin (EPO) in addition to modafinil.
• It shares these pro-motivational effects with other NDRIs like bupropion and methylphenidate and with selective dopamine reuptake inhibitors like modafinil and its analogues.
• Chemically, armodafinil is the enantiopure (R)-(–)-enantiomer of the racemic mixture modafinil (brand name Provigil).
• Modafinil and armodafinil are non-amphetamine alerting drugs originally developed for the treatment of narcolepsy that have been approved by the FDA (the US Food and Drug Administration) for excessive sleepiness associated with SWSD.
• Drugs like modafinil, armodafinil, pitolisant (Wakix), sodium oxybate (Xyrem) oral solution, have been approved as treatment for EDS symptoms in the United States.
• It was from Lafon that Cephalon obtained the rights to modafinil, which it marketed under the trade name Provigil, for the treatment of excessive daytime sleepiness associated with narcolepsy, sleep apnea, and shift work sleep disorder.
• Since then, many substituted phenylpiperidine derivatives have been discovered, hybridizing the basic nocaine structure with that of other similar molecules such as methylphenidate, meperidine and modafinil to create a large family of derivatives with a range of activity profiles and potential applications.
• In 2022, Lepchenko was suspended from tennis for four years (backdated to August 2021), after testing positive for the stimulant adrafinil, and its metabolite, modafinil.
• Psychostimulants such as amphetamine, methylphenidate, and modafinil have been studied in the treatment of CFS.
• Schedule IV includes some weaker barbiturates like (phenobarbital) and other hypnotics, anxiolytic benzodiazepines (except flunitrazepam), and some weaker stimulants (such as modafinil and armodafinil).
• A study published by Cephalon describing research to develop a successor to the eugeroic modafinil reported that the corresponding fluorenol derivative was 39% more effective than modafinil at keeping mice awake over a 4-hour period.
• Still, long-term studies comparing the effectiveness and tolerability of pitolisant with modafinil or sodium oxybate are lacking.
• Dopamine reuptake inhibitors (DRIs) have been grouped into two types, typical or conventional DRIs like cocaine, WIN-35428 (β-CFT), and methylphenidate that produce potent psychostimulant, euphoric, and reinforcing effects, and atypical DRIs like vanoxerine (GBR-12909), modafinil, benztropine, and bupropion, which do not produce such effects or have greatly reduced such effects.
• Various selective DRIs are known, like amineptine, modafinil, and vanoxerine, in contrast to the case of DRAs.
• Drugs that may increase mental energy include caffeine, modafinil, psychostimulants like amphetamines and methylphenidate, and corticosteroids like hydrocortisone and dexamethasone.
• Eugeroics, in the sense of modafinil-type wakefulness promoting agents, include modafinil itself, armodafinil, and adrafinil, among others.
• Analogues of fladrafinil include modafinil, armodafinil ((R)-modafinil), esmodafinil ((S)-modafinil), adrafinil (CRL-40,028; N-hydroxymodafinil), flmodafinil (CRL-40,940; bisfluoromodafinil), and CE-123, among others.
• Pharmacological neuroenhancement agents may include compounds thought to be nootropics, such as modafinil, caffeine, and other drugs used for treating people with neurological disorders.

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