Synonymer & Anagram | Engelska ordet PARACRINE

Exempel på hur man kan använda PARACRINE i en mening

• Cytokines have been shown to be involved in autocrine, paracrine and endocrine signaling as immunomodulating agents.
• Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to cell signaling by endocrine factors, hormones which travel considerably longer distances via the circulatory system; juxtacrine interactions; and autocrine signaling.
• As such, an increase in sodium chloride concentration would result in vasoconstriction of afferent arterioles, and reduced paracrine stimulation of juxtaglomerular cells.
• Leukotrienes use lipid signaling to convey information to either the cell producing them (autocrine signaling) or neighboring cells (paracrine signaling) in order to regulate immune responses.
• Wnt signaling pathways use either nearby cell-cell communication (paracrine) or same-cell communication (autocrine).
• The biological effects produced by intracellular actions are referred as intracrine effects, whereas those produced by binding to cell surface receptors are called endocrine, autocrine, or paracrine effects, depending on the origin of the hormone.
• Cell signaling can occur over short or long distances, and can be further classified as autocrine, intracrine, juxtacrine, paracrine, or endocrine.
• These growth factors often act in a paracrine or autocrine fashion; they include fibroblast growth factor, placental growth factor, insulin-like growth factor, hepatocyte growth factor, and platelet-derived endothelial growth factor.
• In mice, the agouti gene encodes a paracrine signalling molecule that causes hair follicle melanocytes to synthesize the yellow pigment pheomelanin instead of the black or brown pigment eumelanin.
• Cytoplasmic localization of PELP1 upregulates pro-tumorigenic IKKε and secrete inflammatory signals, which through paracrine macrophage activation, regulate the migratory phenotype associated with breast cancer initiation.
• This local action of FGFs (Fibroblast Growth Factors) with their RTK receptors is classified as paracrine signalling.
• M-CSF released by osteoblasts (as a result of endocrine stimulation by parathyroid hormone) exerts paracrine effects on osteoclasts.
• Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
• It binds bone morphogenetic proteins, members of the TGF beta superfamily of ligands, which are involved in paracrine signaling.
• Somatomedins are produced in many tissues and have autocrine and paracrine actions in addition to their endocrine action.
• These cells are responsive to both autocrine and paracrine activin B signaling, which controls their proliferation.
• Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor.
• IL-30 was identified as a cytokine able to condition, in an autocrine or paracrine manner, gene expression profile, at times the viability, motility, and invasiveness of breast cancer cells and to generate an inflammatory and prometastatic milieu supporting tumor growth and progression.
• 2023 Michelle Monje, for her groundbreaking discoveries that neuronal activity promotes adaptive myelination important for cognition, and that neuronal activity drives malignant glioma progression through neuron-to-glioma synapses and paracrine factors.
• It has been shown that in some highly aggressive tumors, such as mesothelioma and melanoma, ABCB5 contributes to multi-drug chemotherapy resistance, and tumor growth, controlling a proinflammatory signaling circuit utilizing TLR4, IL-1β, IL8 and CXCR1 signaling involving reciprocal paracrine interactions between the cancer stem cells and tumor bulk population (in a rheostat manner termed "cancer stem cell rheostasis").

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