Information om | Engelska ordet POLYKETIDES

Exempel på hur man kan använda POLYKETIDES i en mening

• Further studies in 1903 by Collie on the triketone polyketide intermediate noted the condensation occurring amongst compounds with multiple keten groups coining the term polyketides.
• The compounds found in plants are of many kinds, but most can be grouped into four major biosynthetic classes: alkaloids, phenylpropanoids, polyketides, and terpenoids.
• Okadaic acid (OA) and its derivatives, the dinophysistoxins (DTX), are members of a group of molecules called polyketides.
• The enzyme MCAT together with an acyl carrier protein (ACP), and a polyketide synthase (PKS) and chain-length factor heterodimer, constitutes the minimal PKS of type II polyketides.
• They are defined as a subclass of polyketides, having an octahydrotetracene-2-carboxamide skeleton and are known as derivatives of polycyclic naphthacene carboxamide.
• Brevetoxins share the common backbone structure of polyketides, but there are several methyl and oxygen groups that are not typical in traditional polyketide biosynthesis.
• Polyketide synthases (PKSs) are a family of multi-domain enzymes or enzyme complexes that produce polyketides, a large class of secondary metabolites, in bacteria, fungi, plants, and a few animal lineages.
• Rearranging the modular units in natural polyketide synthases, combining modules from different enzymes, and incorporating novel synthetic chemical starter units enabled them to produce a wide variety of novel polyketides that would be difficult to obtain via organic synthesis alone.
• They also specify the initial regiospecific folding and cyclisation pattern of nascent polyketides either through the action of a cyclase (CYC) subunit or through the combined action of site-specific ketoreductase and CYC subunits.
• Lomaiviticins are aromatic polyketides in the angucycline family and share a diazo group similar to kinamycins.
• Trichoderma longibrachiatum produces many secondary metabolites including: peptaibols, polyketides, pyrones, terpenes and diketopiperazine-like compounds.
• Tri- and polyketones are of practical importance as intermediates in the biosynthesis of polyketides.

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