Anagram & Information om | Engelska ordet PSORALEN

Exempel på hur man kan använda PSORALEN i en mening

• Of those, at least 25 species contained a psoralen derivative, either bergapten (5-methoxypsoralen) or methoxsalen (8-methoxypsoralen).
• Psoralen occurs naturally in the seeds of Psoralea corylifolia, and is used in PUVA (psoralen + UVA) treatment, for several diseases including such as psoriasis.
• PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: vitiligo, eczema, psoriasis, graft-versus-host disease, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen.
• Cell cultures produce the coumarins umbelliferone, scopoletin, psoralen, xanthotoxin, isopimpinellin, rutamarin and rutacultin, and the alkaloids skimmianine, kokusaginine, 6-methoxydictamnine and edulinine.
• Chemically, methoxsalen is a derivative of psoralen and belongs to a class of organic natural molecules known as furanocoumarins.
• Psoralen (also called psoralene) is the parent compound in a family of naturally occurring organic compounds known as the linear furanocoumarins.
• Interstrand cross-links are caused by chemicals such as nitrogen mustard and psoralen which create cytotoxic lesions.
• In the European Union, ustekinumab is authorized for the treatment of moderate to severe plaque psoriasis in people above the age of six years whose condition has not improved with, or who cannot use, other systemic (whole-body) psoriasis treatments, such as ciclosporin, methotrexate or PUVA (psoralen ultraviolet A);.
• Ammi majus contains significant amounts of furanocoumarins bergapten and xanthotoxin (also known as methoxsalen), two psoralen derivatives well known for their photosensitizing effects.
• Trioxsalen (trimethylpsoralen (TMP), trioxysalen (INN) or Trisoralen) is a furanocoumarin and a psoralen derivative.
• Bergapten is a derivative of psoralen, the parent compound of a family of naturally-occurring organic compounds known as the linear furanocoumarins (so called since they exhibit a linear chemical structure).
• Numerous therapies have been attempted, with varying degrees of success, such as dermabrasion, CO2 laser, intralesional injections of corticosteroids or hyaluronidase, oral retinoids, psoralen ultraviolet A, and pimecrolimus.
• The use of narrowband UVB and psoralen have shown to be effective treatments for some patients with pigmented purpuric dermatoses.
• Complete excision, psoralen and UVA therapy, intralesional triamcinolone, and high-dose corticosteroids are among the PGA treatment options.
• A PUVA keratosis is a precancerous keratotic skin lesion that arises from exposure to psoralen plus ultraviolet A light therapy.
• Cullen corylifolium extract contains numerous phytochemicals, including flavonoids (neobavaisoflavone, isobavachalcone, bavachalcone, bavachinin, bavachin, corylin, corylifol, corylifolin and 6-prenylnaringenin), coumarins (psoralidin, psoralen, isopsoralen and angelicin), meroterpenes (bakuchiol, and 3-hydroxybakuchiol).
• The surface of the plant is covered in a mix of chemicals including psoralen, xanthotoxin and bergapten that causes a phototoxic reaction resulting in blistering two or three days after exposure.
• It has several potential uses: (i) forage crop, (ii) Phytostabilization of heavy metal contaminated or degraded soils, (iii) Synthesis of furanocoumarins (psoralen, angelicin, xanthotoxin and bergapten), compounds of broad pharmaceutical interest.
• In meantime, tribes in India used Psoralea corylifolia which contained psoralen, the isomer of angelicin.
• It is also indicated for the treatment of moderate to severe chronic plaque psoriasis in adults who failed to respond to, have a contraindication to, or are intolerant of other systemic therapies, including cyclosporine, methotrexate, or psoralen and ultraviolet-A light.

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