Anagram & Information om | Engelska ordet SNPS

Exempel på hur man kan använda SNPS i en mening

• An example of its application is in SNPs arrays for polymorphisms in cardiovascular diseases, cancer, pathogens and GWAS analysis.
• "Variant" may also be used as a general term for any single nucleotide change in a DNA sequence, encompassing both common SNPs and rare mutations, whether germline or somatic.
• QTLs are mapped by identifying which molecular markers (such as SNPs or AFLPs) correlate with an observed trait.
• The HapMap project chose a sample of 269 individuals and selected several million well-defined SNPs, genotyped the individuals for these SNPs, and published the results.
• In single variant tests, it has been shown that SNPs were enriched for variants associated with adiposity, type 2 diabetes, coronary heart disease and kidney function in previously published GWAS, providing evidence that genetic loci related to blood pressure contribute to cardiovascular outcomes.
• In a study of genetic origins, admixture, and asymmetry in maternal and paternal human lineages in Cuba, thirty-five Y-chromosome SNPs were typed in the 132 male individuals of the Cuban sample.
• Current genetics analyses using a genomewide set of single nucleotide polymorphisms (SNPs) has confirmed new subspecies range boundaries for both Dall's and Stone's sheep, updating the previous pelage-based and mitochondrial DNA classifications.
• Furthermore, comparing two genomes not only reveals conserved domains or synteny but also aids in detecting copy number variations, single nucleotide polymorphisms (SNPs), indels, and other genomic structural variations.
• Also, transitions are less likely to result in amino acid substitutions (due to wobble base pair), and are therefore more likely to persist as "silent substitutions" in populations as single nucleotide polymorphisms (SNPs).
• In contrast to previous studies, which only considered small numbers of exonic single nucleotide polymorphisms (SNPs) and did not investigate sex-specific effects, this study used microarray technology to genotype a range of SNPs associated with all four MCPH genes, including upstream and downstream regulatory elements, and allowed for separate effects for males and females.
• With the advent in the mid-2000s of genotyping chips, which could measure hundreds of thousands of single-letter variations (SNPs) across the genome, deCODE statisticians were able to accurately phase segments of the genome - to understand the parental source of segments -  and then impute genotypes measured in some people across the entire population.
• The Y-chromosomes were 1 E (E1b1b1a1b1a), 1 F, 5 G2a (two G2a2b2a1a1b1a1a2 and three more with derived subclades), 19 I1-M253 with SNPs below L1237, Z2039 and P109, 1 I2a1b1, 1 J2b2a1, 1 J2a1a, 2 N1a, 2 R1a1a, 1 with derived R1a-M458, and 6 R1b (three of them with SNPs below U106).
• GenoChip is specifically designed for anthropological testing and includes SNPs from autosomal DNA, X-chromosome DNA, Y-chromosome DNA and mitochondrial DNA (mtDNA).
• This is in contrast to genome-wide association studies (GWAS), which is a hypothesis-free approach that scans the entire genome for associations between common genetic variants (typically SNPs) and traits of interest.
• QTL positions are automatically assigned based on the genomic positions of peak and/or flanking markers or single nucleotide polymorphisms (SNPs).
• Therefore, the number of markers (one of two or more known variants in the genome at a particular location – known as Single-nucleotide polymorphisms or SNPs) inherited from a specific ancestor decreases by about half with each successive generation; that is, an individual receives half of their markers from each parent, about a quarter of those markers from each grandparent; about an eighth of those markers from each great-grandparent, etc.
• It found two different mutations, each containing only a variation in only one nucleotide (called single nucleotide polymorphisms, or SNPs), which were associated with ARMD.
• In genotyping studies where DNA is directly assayed for positions of variance (see SNP), concordance is a measure of the percentage of SNPs that are measured as identical.
• The process of recombination, if frequent enough, corrupts the ability to create parsimonious trees because of stretches of amino acid subsititions (SNPs).
•   Over the next fifteen years they used standard GWAS and reduced fecundity as an intermediate phenotype to home in on SNPs and copy number variations (CNVs) linked to risk of schizophrenia and other disorders;  they demonstrated that genetic risk factors for schizophrenia and autism confer cognitive abnormalities even in control subjects;  they linked schizophrenia, bipolar disorder with both creativity and risk of addiction;  they identified genetic variants associated with educational attainment and childhood cognition; and demonstrated that these variants are currently under negative evolutionary selection.

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