Information om | Engelska ordet TNBC

Exempel på hur man kan använda TNBC i en mening

• Targeted at kids and teens, Saved by the Bell was broadcast in the United States on Saturday mornings, later as the flagship series in NBC's TNBC lineup.
• Trying to hammock programs that have little in common with each other can have unusual consequences: TNBC, a block of programming NBC carried during the 1990s that had been aimed at teenagers, had a lead-in from Weekend Today, a news program targeting those teens' parents.
• Created by Troy Searer, Robert Tarlow and Mark Fink, the series featured extensive cast changes throughout its six-season run, similar to its TNBC stablemate.
• Younger women have a higher rate of basal or BRCA related TNBC, while older women have a higher proportion of apocrine, normal-like and rare subtypes including neuroendocrine TNBC.
• Young Hispanic women, premenopausal women, and women who test positive for the BRCA1 gene mutation, also have a higher prevalence of TNBC diagnosis.
• In a study presented at the 2024 American Association for Cancer Research (AACR) Annual Meeting, researchers introduced rabbit polyclonal antibodies specifically targeting ZIP7 to both human triple-negative breast cancer cells (TNBC) and normal breast epithelial cells (NBE) obtained from the same patient.
• In triple-negative breast cancer (TNBC), oncogenic activation of the PI3K/AKT/mTOR pathway can happen as a function of overexpression of upstream regulators like EGFR, activating mutations of PIK3CA, loss of function or expression of phosphatase and tensin homolog (PTEN), and the proline-rich inositol polyphosphatase, which are downregulators of PI3K.
• Different primitive and metastatic TNBC cancer mouse models were established in mice, and the treatment CIK cells plus cetuximab significantly restrained primitive tumor growth in mice, either in patient-derived tumor xenografts or MDA-MB-231 cell line models.
• Atezolizumab, sold under the brand name Tecentriq among others, is a monoclonal antibody medication used to treat urothelial carcinoma, non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), hepatocellular carcinoma and alveolar soft part sarcoma, but discontinued for use in triple-negative breast cancer (TNBC).

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